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Transcriptional and Translational Regulation of Stem Cells

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Transcriptional and Translational Regulation of Stem Cells

Helen Abud, Gary Hime

Springer
Collection: Advances in Experimental Medicine and Biology
Publication date : 2013-05-22

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This volume describes the latest findings on transcriptional and translational regulation of stem cells. Both transcriptional activators and repressors have been shown to be crucial for the maintenance of the stem cell state. A key element of stem cell maintenance is repression of differentiation factors or developmental genes – achieved transcriptionally, epigenetically by the Polycomb complex, and post-transcriptionally by RNA-binding proteins and microRNAs. This volume takes two approaches to this topic – (1) illustrating the general principles outlined above through a series of different stem cell examples – embryonic, iPS and adult stem cells, and (2) describing several molecular families that have been shown to have roles in regulation of multiple stem cell populations.

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About the book

Author

Helen Abud , Gary Hime

Imprint

Springer

Collection

Advances in Experimental Medicine and Biology

Publication date

2013-05-22

Pages

371 pages

Print ISBN

9789400766204

Language

English

Ebook informations

EAN EPUB

9789400766211

Price

£129.50

Copy count 3

Print count 37

File size 4393 Ko

Informations accessibility

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About author(s)

Helen Abud

Gary Hime

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