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Trials for Cerebellar Ataxias

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Trials for Cerebellar Ataxias

From Cellular Models to Human Therapies

Alexis Brice, Mario Manto, Stefan M. Pulst, Bing-Wen Soong, Stefan M. Pulst

Springer
Collection: Contemporary Clinical Neuroscience
Publication date : 2023-05-29

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Despite the critical importance of the cerebellum in brain function, the scientific community still lacks effective treatments for most cerebellar ataxias. This book provides a link between the pathogenesis and therapies of cerebellar ataxias while also providing a comprehensive assessment of the preclinical and clinical trials dedicated to cerebellar ataxias over the past 20 years of progress. This is the first book fully dedicated to the trials and therapies of these disorders. It is a truly authoritative and comprehensive reference, and comes at a time of major advances in genetic tools and neuroimaging assessments. The coverage begins by laying a foundation of the basic science of the cerebellum and ataxias, proceeds to discuss biomarkers and the tools of trials, offers guidelines on conducting trials, and then explores the full range of therapeutics and their trials, including gene therapy and cell transplantation. The authors are top experts on cerebellar research and the contributing authors have all made seminal contributions in the field.

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About the book

Author

Alexis Brice , Mario Manto , Stefan M. Pulst , Bing-wen Soong , Stefan M. Pulst

Imprint

Springer

Collection

Contemporary Clinical Neuroscience

Publication date

2023-05-29

Pages

727 pages

Print ISBN

9783031243448

Language

English

Ebook informations

EAN PDF

9783031243455

Price

£199.99

Copy count 7

Print count 72

File size 28908 Ko

Informations accessibility

EAN EPUB

9783031243455

Price

£199.99

Copy count 7

Print count 72

File size 34744 Ko

Informations accessibility

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About author(s)

Alexis Brice

Mario Manto

Stefan M. Pulst

Bing-wen Soong

Stefan M. Pulst

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