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Structure and Function
Louise Reader
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This volume in the Subcellular Biochemistry (SCBI) series is a continuation of several previous volumes devoted to the structural and functional study of protein complexes. The expanding nature of this field of study, derived mainly from X-ray crystallography and electron cryomicroscopy, justifies the continuing expansion of coverage in an almost encyclopaedic manner within the SCBI series.
Experienced and active researchers in the field shed light on the biology of protein complexes involved in important cellular functions from different perspectives, such as AcrAB-TolC, and CST. Other topics covered are: the Toxin-Antitoxin systems in cell survival, the role of the ATPases CueR and RUVBL1-RUVBL2 in the regulation of gene expression, complexes with multiple functions in the cell such as VCP/p97 or the Vault complex, FtsA and FtsZ in bacterial cell division, GATOR1 and GATOR2 in amino acid sensing, TRPA1 and the Serotonin Transporter in signaling, oligomeric structures in eukaryotic cells such as amyloids and invertases, among others.
The book is richly illustrated, the result of an impressive integration of structural data from X-ray crystallography and cryo-electron microscopy. Functional aspects of protein-protein interactions are also featured prominently, providing a valuable contribution for researchers and scholars.
Chapter 13 is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
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J. Robin Harris is a retired structural biologist and electron microscopist. He is an Honorary Professor of the University of Mainz, Germany, where he worked with the group of Professor Juergen Markl, in the Institute of Zoology. Since taking retirement, Robin continued part-time research for several years at the Newcastle University, UK, and acted as an Editor of the Elsevier journal micron and as Series Editor of the long-standing Springer book series Subcellular Biochemistry.
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