Redox Signaling in Wound Healing in Elderly Populations: Clinical Approach, Part 2

Redox Signaling in Wound Healing in Elderly Populations: Clinical Approach, Part Two, Volume Three covers wounds in different types and locations (diabetic, ischemic, post-operational) in subcellular and macro dimensions, examining their relationship with aging with an aim to target deteriorating redox signaling cascades and highlight promising therapeutic approaches. Understanding the indication for the use of new therapeutics targeting the illuminated pathways in wound healing helps adjust treatment regimens befitting modern medicine. Ineffective redox adaptation and disseminated oxidative injury are the hallmarks of continuing oxidative stress.However, oxidative stress cannot be simply described as the imbalance between ROS formation and antioxidant defense capacity. This also covers impairment in redox sensing and signaling pathways. The term oxidative stress is an expression that is losing its use in modern redox biology. It is now an accepted fact that ROS cannot be described as an apparent enemy or friend. Its optimum level modulates signal transduction and stress responses by acting as a second messenger for redox-sensitive cascades. - Provides the only source that accounts for all of the intracellular and intercellular redox homeostasis, cascades, and mechanisms of wound healing in elderly people - Deals with wounds in different types and locations (diabetic, ischemic, post-operational) in subcellular and macro dimensions - Examines wound healing and its relationship with aging - Helps adjust redox-based treatment regimens befitting modern medicine