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Transporters in Drug Discovery and Development

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Transporters in Drug Discovery and Development

Detailed Concepts and Best Practice

Yurong Lai

Woodhead Publishing
Publication date : 2014-08-22

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Written by a leading researcher in the field, Transporters in Drug Discovery and Development provides a comprehensive and practical guide to drug transporter families that are the most important for drug discovery and development. It covers: an overview of transporter families and organ distribution; clinical relevant drug-drug interaction; clinical relevant polymorphism; drug transporter related pharmacokinetic, pharmacodynamics and toxicity; in vitro/in vivo probes of drug transport studies; the practical methodologies of industrial transporter screening and translational aspect in drug discovery and developments. - A comprehensive overview of drug transporter families and their clinical relevance in drug discovery and development - Balanced coverage of molecular biology aspects and functional outcomes - State of art knowledge related to transporter-mediated DDI and the clinical relevance in pharmacokinetics, dynamics, and toxicity

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About the book

Author

Yurong Lai

Imprint

Woodhead Publishing

Collection

n.c

Publication date

2014-08-22

Pages

780 pages

Print ISBN

9781907568213

Language

English

Ebook informations

EAN PDF DRM-FREE

9781908818287

Price

£189.90

Informations accessibility

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About author(s)

Yurong Lai

Yurong Lai is a senior principal scientist at a US-based pharmaceutical company. He received his M.D. from Fujian Medical University in China and a Ph.D. (Toxicology) from Sapporo Medical University in Japan. From 1998 to 2001, he was a research fellow of Japanese Society for Promotion (JSPS) in Department of Physiopathology, Graduate School of Medicine of Hokkaido University, followed by a position as Research Associate in Department of Pharmaceutics, University of Washington

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