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Chemokine Receptors as Drug Targets

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Chemokine Receptors as Drug Targets

Rob Leurs, Sergio A. Lira, Martine J. Smit

Wiley-VCH
Collection: Methods & Principles in Medicinal Chemistry
Publication date : 2010-09-23

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Chemokines are hormone-like signaling molecules secreted by cells to signal infection and guide the immune response. Following a decade of basic chemokine research, the pharmaceutical industry has now begun to exploit this crucial signaling pathway for the development of innovative drugs against AIDS, cancer, neural and autoimmune diseases. Here is the first reference focusing on these novel drug development opportunities.
Opening with a general introduction on chemokine function and chemokine receptor biology, the second part covers the known implications of these signaling molecules in human diseases, such as cancer, neural disorders, and viral infection, including AIDS. The third part systematically surveys current drug development efforts at targeting individual chemokine receptors, as well as other chemokine interaction partners, including up-to-date reports from the pharmaceutical industry.

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About the book

Author

Rob Leurs , Sergio A. Lira , Martine J. Smit

Imprint

Wiley-VCH

Collection

Methods & Principles in Medicinal Chemistry

Publication date

2010-09-23

Pages

408 pages

Print ISBN

9783527321186

Language

English

Ebook informations

EAN PDF

9783527632008

Price

£159.25

Copy count 0

Print count 408

File size 5714 Ko

Informations accessibility

EAN EPUB

9783527632343

Price

£159.25

Copy count 0

Print count 408

File size 2970 Ko

Informations accessibility

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About author(s)

Rob Leurs

Sergio A. Lira

Martine J. Smit

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