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Comprehensive Analysis of Parasite Biology

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Comprehensive Analysis of Parasite Biology

From Metabolism to Drug Discovery

Rachel Cerdan, Sylke Müller, Ovidiu Radulescu

Wiley-Blackwell
Collection: Drug Discovery in Infectious Diseases
Publication date : 2016-07-19

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Written and edited by experts in the field, this book brings together the current state of the art in phenotypic and rational, target-based approaches to drug discovery against pathogenic protozoa. The chapters focus particularly on virtual compounds and high throughput screening, natural products, computer-assisted drug design, structure-based drug design, mechanism of action identification, and pathway modelling. Furthermore, state-of the art "omics" technologies are described and currently studied enzymatic drug targets are discussed. Mathematical, systems biology-based approaches are introduced as new methodologies for dissecting complex aspects of pathogen survival mechanisms and for target identification. In addition, recently developed anti-parasitic agents targeting particular pathways, which serve as lead compounds for further drug development, are presented.

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About the book

Author

Rachel Cerdan , Sylke Müller , Ovidiu Radulescu

Imprint

Wiley-Blackwell

Collection

Drug Discovery in Infectious Diseases

Publication date

2016-07-19

Pages

576 pages

Print ISBN

9783527339044

Language

English

Ebook informations

EAN PDF

9783527694099

Price

£162.42

Copy count 0

Print count 576

File size 8899 Ko

Informations accessibility

EAN EPUB

9783527694112

Price

£162.42

Copy count 0

Print count 576

File size 13097 Ko

Informations accessibility

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About author(s)

Rachel Cerdan

Sylke Müller

Ovidiu Radulescu

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