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Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates

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Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates

Al Postigo

Elsevier
Publication date : 2018-09-05

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Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates reviews how the use of these techniques on compounds with already known and relevant biological activity can provide new pharmaceutical leads with improved medicinal properties. The fluorination strategies discussed take into account both conventional and novel reagents, including nucleophilic, electrophilic, those of a radical nature, and diverse families of organic compounds, such as (hetero) aromatic rings and aliphatic substrates. Drawing on the authors' expert knowledge, this book provides researchers with a broad set of applicable methods to use in their work. - Highlights the latest developments in the field in a concise volume - Provides details of key fluorinating reagents across diverse families of organic compounds - Explores the current applications and future potential of fluorine in drug development

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About the book

Author

Al Postigo

Imprint

Elsevier

Collection

n.c

Publication date

2018-09-05

Pages

390 pages

Print ISBN

9780128129586

Language

English

Ebook informations

EAN EPUB DRM-FREE

9780128130391

Price

£184.63

Informations accessibility

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About author(s)

Al Postigo

Professor Postigo has worked at the University of Buenos Aires since 2010, where he teaches in the faculty of pharmacy and biochemistry. Having completed his MSc at the University of Buenos Aires, he then took up a place at McMaster University, Canada, where he completed his Doctoral studies in Organic Chemistry. With a particular research interest in fluorination, he has contributed to over 50 publications across the top journals in the field.

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