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This book discusses recent research in innate immunity, which has revealed a large number of receptors that sense the presence of microorganisms or cellular damage in tissues. In complex tissues, many of these sensing events occur simultaneously. Thus, the downstream...
This book is about the transformation of the biomedical information to smart healthcare, the chapters are designed to discuss the health associated factors such as genetics, lifestyle, nutrition and environmental factors. The interactions of these factors and the...
This second edition of the book on Store-operated Ca2+ Entry Pathways has been updated with the newest discoveries that emerged in the field within the last five years. The crystal structure of the Ca2+ signaling core complex is described which adds to a new...
This book offers a broad overview of the concepts and research findings in immunometabolism. The immune system is made up of numerous different cell types, pathways, and components that must be able to respond rapidly to a pathogen or cancer, but must also remain...
This book is the first comprehensive review of drebrin, which plays pivotal roles in various cellular events, via forming unique actin cytoskeletons, including synapse formation and in synaptic function. Particularly the loss of drebrin from dendritic spines is used as...
The mammalian genome is constantly challenged by exogenous and endogenous threats. Although much is known about the mechanisms that maintain genome integrity, little is known about the applications of this knowledge to combat human disease.The past 20 years has...
This book is a blend of medical research and clinical practice. Advancements in practice are inextricably bound to have research underpinnings. The articles highlight a range of practical topics. The respiratory tract is upfront as the first line of defense of the...
This book provides the first comprehensive coverage of the quickly evolving research field of membrane contact sites (MCS). A total of 16 chapters explain their organization and role and unveil the significance of MCS for various diseases. MCS, the intracellular...
This contributed volume offers a comprehensive and detailed overview of the various aspects of long non-coding RNAs and discusses their emerging significance. Written by leading experts in the field, it motivates young researchers around the globe, and offers graduate...
Hereditary tyrosinemia type 1 (HT1), the most severe inborn error of the tyrosine degradation pathway, is due to a deficiency in fumarylacetoacetate hydrolase (FAH). The worldwide frequency of HT1 is one per 100,000 births, but some regions have a significantly higher...
This book offers an essential guide to RNA activation (RNAa), an emerging and fascinating new field. RNAa is a small RNA-guided and Argonaute-dependent gene regulation phenomenon in which promoter-targeted short double-stranded RNAs (dsRNAs) induce target gene...
This book series focuses on current progress in the broad field of medical microbiology, and covers both basic and applied topics related to the study of microbes, their interactions with human and animals, and emerging issues relevant for public health. Original...
Due to the resultant health consequences and considerable increase in prevalence, obesity has become a major worldwide health problem. “Obesity and Lipotoxicity” is a comprehensive review of the recent researches to provide a better understanding of the...
Both communicable and noncommunicable diseases of the respiratory system are an increasing healthcare problem despite medical advances. This book aims at unraveling the mechanisms and improving the treatment of pulmonary pathologies, ranging from such common conditions...
Numerous studies have shown that elevated levels of circulating tumor cells (CTCs) in blood of cancer patients are associated with poor response to treatment and inferior survival probabilities. Despite this clinical significance, the molecular biology of CTCs remains...
Respiratory infections constitute a major public health concern. The goal of this book is to share knowledge on the best advances in influenza and influenza-like viral infections, and new molecular-based diagnostic methods that discern the...
This book discusses Prosthetic Joint Infection (PJI), which remains one of the most common problems necessitating revision arthroplasty. It pursues a multidisciplinary approach, bringing together opinions from the leading experts in the field. The book identifies the...
This book discusses the latest findings on the physiological and pathological functions of transient receptor potential canonical/classical (TRPC) proteins in the brain. In addition to reviewing the functions of TRPCs in brain development and neuron...
The chapters in this topical volume of Advances in Microbiology, Infectious Diseases and Public Health present exciting, insightful observations on emerging viral infections like influenza, Middle East respiratory syndrome, or mosquito-transmitted diseases, as well as...
Hypertension: from basic research to clinical practice” contains a unique collection of selected chapters written by experts and enthusiasts engaged in research and treatment of hypertension, a condition that affects around a billion people in the world. The chapters...
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