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Taxol®, a naturally occurring diterpenoid is one of the most exciting antitumor drugs available today. Its current indications (refractory ovarian and metastatic breast cancer) may soon be expanded since the drug is showing activity against lung and head-and-neck...
A comprehensive and consolidated account of how microorganisms can play a significant role in degrading and detoxifying toxic, carcinogenic, mutagenic, and teratogenic compounds is detailed in this book. Moreover, the volume deals with all aspects of microbial...
This book concentrates on the organizational level of neurons and neuronal networks under the unifying theme "The Self-Organizing Brain - From Growth Cones to Functional Networks". Such a theme is attractive because it incorporates all phases in the emergence of...
This hundredth volume is a commemorative milestone in the prestigeous Progress in Brain Research series. Accordingly, authors were invited to write on any topic, given that their choice represented the topic most near and dear to their own efforts over a significant...
This book contains six chapters, each of which is a self-contained, thorough review by an expert in the field of a particular topic in medicinal chemistry, bacteriology or pharmacology. Each topic is a currently active subject of research in either the quest for new...
This book focuses on the role of gangliosides in three areas of medicine in which rapid progress has been made in the last decade: cancer, peripheral neuropathies and Alzheimer's disease. The volume further reflects progress in the pathogenesis of peripheral...
Chemical Signalling in the Basal Ganglia
Cholinergic Function and Dysfunction
Natural and Artificial Control of Hearing and Balance
In this volume, the medicinal chemistry of the rapidly expanding family of retinoids, of promising semi-synthetic erythromycins and of the multifaceted amidines is reviewed. Another chapter continues the coverage of inorganic elements which have a medical role; recent...
In the eight years since the publication of Volume 63 of Progress in Brain Research, on this subject, developments in the research field have been very fast. For example, receptor physiology and pharmacology is now an intensively studied field, and the excitotoxic...
This timely new volume presents broad-based and wide-ranging contributions on all aspects of vision. The material is grouped for presentation in a logical fashion in five main themes: peripheral processing; sensory integration in superior colliculus; organization of...
The Human Hypothalamus in Health and Disease
Circumventricular Organs and Brain Fluid Environment
GABA in the Retina and Central Visual System
The 29th volume of the series presents yet again, an exemplary survey of a wide range of current topics in medicinal chemistry and pharmacology. Eight expert reviews emphasize the relationships between chemical structure and pharmacological activity. These detailed...
Neurobiology of the Locus Coeruleus
The six reviews in this volume cover once again a most comprehensive range of topics.The anti-malarial activity of the 8-aminoquinolines is examined, with an eye to the development of a single, broad-spectrum drug. Chelation, important in removal of toxic metals from...
Thanks to a resurgence of interest and a recent proliferation of research techniques, much new and illuminating data has emerged during the last decade relating to the prefrontal cortex, particularly in primates and rodents. In view of this progress, the 16th...
Afferent Control of Posture and Locomotion
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