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This volume outlines the current status in the field of biomimetic medical materials and illustrates research into their applications in tissue engineering. The book is divided into six parts, focusing on nano biomaterials, stem cells, tissue engineering, 3D printing,...
This book focuses on the biological mechanisms of minimal residual disease (MRD) and recurrence. It integrates this biology in solid cancers and in hematological malignancies. It reports also on technological advancements for monitoring MRD, derived from mechanistic...
The book addresses the development of muscle atrophy, which can be caused by denervation, disuse, excessive fasting, aging, and a variety of diseases including heart failure, chronic kidney diseases and cancers. Muscle atrophy reduces quality of life and increases...
This book systemically describes the mechanisms underlying the neural regulation of metabolism. Metabolic diseases, including obesity and its associated conditions, currently affect more than 500 million people worldwide. Recent research has shown that the neural...
This book covers multi-scale biomechanics for oncology, ranging from cells and tissues to whole organ. Topics covered include, but not limited to, biomaterials in mechano-oncology, non-invasive imaging techniques, mechanical models of cell migration, cancer cell...
The book illustrates how biostatistics may numerically summarize human genetic epidemiology using R, and may be used successfully to solve problems in quantitative Genetic Epidemiology Biostatistics for Human Genetic Epidemiology provides statistical...
The second of two companion books which address the biology and clinical aspects of prostate cancer. This volume, Prostate Cancer: Molecular & Diagnostic Imaging and Treatment Stategies, discusses both classic and the most recent imaging approaches...
This book reviews the scientific literature and the authors’ own research linking aluminum neurotoxicity with cognitive impairment and Alzheimer’s disease (AD). It focuses on aluminum levels in the brain, region-specific and subcellular distribution, and its relation to...
This book introduces readers to the latest technological advances in the emerging field of intelligent orthopaedics. Artificial intelligence and smart instrumentation techniques are now revolutionizing every area of our lives, including medicine. The applications of...
This book summarizes the latest advances in pain research. All the chapters were contributed by speakers from Asian Pain Symposium (APS) on Acute and Chronic Pain, which was held in Taipei in 2017. Founded in Kyoto, Japan in 2000, the APS serves as a platform for...
This book comprehensively describes biological phenomena, adaptation mechanisms, and strategies of living organisms to survive under extremely cold or desiccated conditions at molecular, cellular, and organ levels. It also provides tremendous potential for applications...
This book provides an essential overview of the rapidly advancing field of circular RNAs – newly discovered RNAs that are generated by back-splicing precursor mRNA and perform regulatory functions in many biological processes. Although many aspects of circular RNAs’...
This book on cardiac extracellular matrix (ECM) features three sections, Fundamental Science, Pre-Clinical and Translational Science, and Clinical Applications. In the Fundamental Science section, we will cover the spectrum of basic ECM science from ECM’s role in...
This book provides an overview of recent advances in the study of aging and aging related diseases, discussing the topics at individual, organ, tissue, cell, and molecular levels. It also presents studies on the biomarkers of aging and anti-aging...
This book offers an in-depth and comprehensive review on current understanding of regulatory ncRNAs in complex diseases from a view of bioinformatics. It conveys state-of-the-art bioinformatics tools and methods for ncRNAs from computational detection, functional...
Research into and interest in the role of stromal cells in immunology has exploded over the past 15 years. The conventional view that placed non-hematopoietic stromal cells as passive, structural, and supportive entities has now been replaced with an appreciation that...
Much research has focused on the basic cellular and molecular biological aspects of stem cells.Much of this research has been fueled by their potential for use in regenerative medicine applications, which has in turn spurred growing numbers of translational and clinical...
This volume highlights recent breakthroughs in the interdisciplinary areas of synthetic biology, metabolic engineering and bioprocess engineering for the production of green chemicals. It also presents practical experimental and computational tools for the design,...
This book gathers together contributions from internationally renowned authors in the field of cardiovascular systems and provides crucial insight into the importance of sex- and gender-concepts during the analysis of patient data.This innovative title is the first to...
This book provides a comprehensive review of the major barriers to HIV cure and vaccine. It covers the fundamental virology and immunology leading to HIV transmission, protection from infection and long term HIV persistence on antiretroviral therapy. In addition,...
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