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The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results.The Novartis...
Much research has attempted to show direct linear relations between genes and disorder. However, scientists have been discouraged by inconsistent findings based on this simple gene-phenotype approach. The alternative approach is to incorporate information about the...
This book is a comprehensive and up-to-date account of where we stand in immunological strategies for preventing or treating type 1 diabetes (T1D). Brings together contributions from the leaders in the arena of clinical immunotherapy, not limited to the diabetes field...
Insect-Plant Interactions and Induced Plant DefenceChair: John A. Pickett, 1999 This book examines the sophisticated mechanisms that plants use to defend themselves against attack by insects and pathogens, focusing on the networks of plant signalling pathways that...
Gramicidin and Related Ion Channel-Forming Peptides Chair: Bonnie Wallace 1999Gramicidin channels have been studied intensively for more than 25 years as model transport systems for large protein ion channels, high resolution structural information on which is difficult...
'Homology' as a concept became increasingly elusive during the course of the 20th century. The central debates and controversies concern both fundamental definitions and the nature of the criteria by which homology is judged. Attempts to move away from comparative...
Rice is the most important food crop for half the world's population. Over the last three decades, the imporvement in human nutrition and health in Asia has largely been attributable to a relatively stable and affordable rice supply. The challenge to produce enough rice...
Brings together key new results of interdisciplinary collaborations among various research fields on rhodopsin including the photoreceptive mechanism of rhodopsins, the molecular mechanism of the visual transduction process, visual processes in the retina and other...
A comprehensive volume examining the fundamental questions raised by reductionists' theory about levels of explanation necessary to understand biological systems. The book evaluates the enormously powerful techniques of molecular biology, and analyzes precisely how...
Telomeres and TelomeraseChairman: Sydney Brenner, 1997Telomeres are the protective genetic elements located at the ends of chromosomes and are essential for correct chromosomal structure and function. They are not fully replicated by the conventional DNA polymerase...
This book brings together material on all aspects of immunological tolerance. Basic mechanisms of tolerance are examined in detail, including mechanisms of peripheral T cell tolerance, molecular and genetic mechanisms for maintaining self tolerance, partial T cell...
Sensory Guidance of MovementChairman: Mitchell Glickstein, 1998 In the past few years there has been an increasing recognition of the multiplicity of sensory and motor areas of the cerebral cortex. However, still relatively little is known about the way in which sensory...
The molecular mechanisms and protein species associated with the mineralization of mature dental enamel are active areas of research. This book focuses on specific areas of research including the structural chemistry, protein biochemistry and genetics of enamel...
A timely volume dealing with the evolutionary and structural links between the clotting and fibrinolytic proteins and plasminogen-related growth factors. The role of individual domains for enzymatic proteins and plasminogen-related growth factors is also comprehensively...
The use of oligonucleotides as therapeutic agents rests upon their ability to interfere, in a sequence-specific manner, with the fundamental machinery of protein synthesis either by binding to the mRNAs transcribed from a gene or by binding directly to a target gene....
This up-to-the-minute account examines how radionuclides affect human health. It explores how radionuclides travel through various food chains and how they are transported throughout the terrestrial and aquatic environments.
Epigenetics pertains to the development of an organism from an undifferential cell, resulting in the successive formation and development of organs and parts that did not pre-exist in the fertilized egg. An exciting and stimulating volume which used the extensive...
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