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Connects classical cellular descriptive studies with more recent work on the molecular and genetic aspects regarding germline development. Prominent scientists discuss research on a range of organisms including insects, worms, birds, fish, amphibia, mammals and green...
Drawing together contributions from a diverse group of international experts in the field, this collection of papers examines the biology and pathology of elastin at the molecular level. Topics include the structure, ultrastructure and function of elastin; elastin...
Renowned contributors provide comprehensive coverage of calcium gradients, waves and oscillations in diverse systems. Discusses the mechanisms initiating and sustaining calcium waves and their role in cell function. Describes studies using the latest techniques for...
Cocaine poses interesting problems for neurophysiologists and neuropharmacologists and there is important new data on the effects of cocaine on the brain (its initial site of action at the cellular level now appearing to be the dopamine transporter). Includes chapters...
Examines the establishment of the germ layers and other cell lineages in the early embryo including details of cell movements during the beginning stages of primitive streak formation. Discusses patterns of gene expression during the development of such tissues as the...
Prominent contributors address issues regarding the toxicity of aluminum which causes an encephalopathy in renal dialysis patients and is also known to damage animals and plants via acid rain. Examines the chemistry and biology of aluminum compounds focusing on the...
Documents the latest results and opinions on the causes and possible cures for this disorder. Coverage includes retroviral involvement, immunity, pathophysiology and pharmacological treatment of chronic fatigue syndrome.
Comprised of the latest developments in cell cycle research, it analyzes the principles underlying the control of cell division. Offers a framework for future investigation, especially that aimed toward understanding and treatment of cancer.
Contains the presentations and discussions that took place during a symposium at the CIBA Foundation on October 1-3, 1990 on the subject of catalytic antibodies. The recognition that monoclonal antibodies can possess catalytic activity is a recent advance with profound...
Discusses the various theories of consciousness from different perspectives: psychological, neurophysiological and philosophical. Theories regarding the interaction of pain, schizophrenia, the brain and the nervous system with consciousness are included. Also includes a...
Working on Corticotropin-Releasing Factor in a variety of systems, experts present a coherent depiction of this peptide's role in the control and coordination of the response to stress-inducing situations.
How the amino acid sequence of a protein determines its three-dimensional structure is a major problem in biology and chemistry. Leading experts in the fields of NMR spectroscopy, X-ray crystallography, protein engineering and molecular modeling offer provocative...
A panel of internationally renowned experts present papers on cell signalling--an area in which there has been recent important advances. Coverage includes the inositol 1, 4, 5-triphosphate receptor, signal-induced phospholipid degradation cascade and protein kinase C...
An international group of leading investigators discuss recent progress of sensory structures in lower and higher vertebrates. Experts in two relevant fields--the cell cycle and mitogenic growth factors--present insightful contributions in the search for precursors...
Details the application of positron emission tomography (PET) to the mapping of human cerebral cortical function. Coverage includes all aspects of PET technology. Includes chapters on somatosensory, motor and visual systems, and higher-order processes such as attention,...
Experts from a variety of areas compare and discuss IL-6 and LIF in order to provide a new understanding of their modes of action, the significance of their polyfunctionalization--why the body chooses to use one molecule to regulate various cell types--and their...
Examines the progress of leading scientists working on various aspects of handedness in order to consider the occurrence of handedness in the biological world. Provides in-depth coverage of the origin and development of morphological asymmetry occurring in most types of...
A comprehensive review of current thinking on the biosynthesis, function and evolution of secondary metabolites in animals, plants and microorganisms. Examines the traditional context of secondary metabolites as natural products having no obvious part to play in the...
Using a multidisciplinary approach, it combines anatomical, cellular and physiological studies by preeminent experts. Features important insights into the function of the hypothalamus.
Discusses those aspects of environmental change which might have direct or indirect effects on human health. Includes discussions on water pollution, agricultural pollution, genetic disease and exotic tropical diseases as well as human nutrition and population growth.
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