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Oxidative stress is an imbalance caused by the body's failure to effectively eliminate reactive products generated from the formation of reactive oxygen species (ROS) during cellular metabolism. ROS, reactive nitrogen species (RNS), and RSS are the three primary categories of oxidants produced within the body.
This book summarizes the challenges and limitations of targeting oxidative stress. In addition, the chapters discuss the impact of different oxidants and oxidative stress in different fields of human disease, especially as a global therapeutic to treat various chronic disease managed with drugs. Furthermore, this book explores a wide range of promising approaches and explores the mechanism behind the oxidative stress based on pharmacological properties and highlights its application in the medical field. It serves as a resource for graduates, clinical researchers, industry professionals, and anyone working on antioxidant activity of enzymes or understanding the role of oxidative stress in diseases like cancer.
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Dr Nidhi Srivastava is currently working as an Associate Professor and Head of the department, Biotechnology, at National Institute of Pharmaceutical Education and Research, Raebareli (NIPER-R). She has 22 years of experience in teaching and research post-Ph.D. She has been conducting research on Phyto-therapeutics in the context of microbial infections, neurodegenerative diseases, and cancer.She has published more than 160 research papers in reputed journals, authored six books, and written 24 book chapters. She has supervised more than 45 postgraduate dissertations and 18 Ph.D. scholars, with 17 Ph.D. degrees awarded under her supervision..She holds four granted patents, with an additional three published. She has delivered numerous invited lectures and presented her research at various national and international conferences. Her administrative and research work has been recognized at various national and international forums.
Prof. Shubhini A. Saraf currently serves as the Director of the National Institute of Pharmaceutical Education and Research (NIPER), Raebareli, India. Prior to this, she was a Professor in the Department of Pharmaceutical Sciences and Director (R&D) at Babasaheb Bhimrao Ambedkar University (A Central University), Lucknow. Prof. Shubhini's academic journey began forty years ago at the Department of Pharmaceutical Sciences, Dr. Harisingh Gour University, Sagar, India, where she completed her B. Pharm, M. Pharm, and Ph.D. in Pharmaceutical Sciences. With over 28 years of teaching and research experience, she has made significant contributions to the field. Her research interests include lipid nanoparticles, nanotechnology through material science research, principles of green nanotechnology, drug targeting approaches, various techniques and the regulation of cellular markers as indicators of health status. Her work has had a profound impact on the field. She is also actively involved in healthcare technology policy interventions. Prof. Shubhini has an impressive publication record, with more than 180 papers, 8 books and 22 book chapters to her credit.
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