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It is evident that a defective or deregulated complement system results in kidney diseases. An important role of complement effector and regulatory proteins in pathological settings of the kidney has been demonstrated. A large panel of distinct human kidney diseases is...
Research on, and interest in, red blood cell formation spans several centuries and was thought to have peaked in the 1980s with the cloning of the eryth- poietin (EPO) gene. In the years subsequent to the cloning of EPO and its expression as a recombinant protein, much...
Lie Theory: Unitary Representations and Compactifications of Symmetric Spaces, a self-contained work by A. Borel, L. Ji and T. Kobayashi, focuses on two fundamental questions in the theory of semisimpleLie groups: the geometry of Riemannian symmetric spaces and their...
Semisimple Lie groups, and their algebraic analogues over fields other than the reals, are of fundamental importance in geometry, analysis, and mathematical physics. Three independent, self-contained volumes, under the general title of Lie Theory, feature survey work...
The extraordinary range of cultural interests of renowned physicist David Speiser—including the sciences, art, architecture, music, and history of science—has inspired generations of later scientists to look beyond the boundaries of their own disciplines. In this book,...
Many breast tumours are dependent upon oestrogen for their development and continued growth. Over the last 25 years hormone therapy has progressed from the irreversible destruction of endocrine glands to the use of drugs that reversibly suppress oestrogen synthesis or...
In the processes studied in contemporary physics one encounters the most diverse conditions: temperatures ranging from absolute zero to those found in the cores of stars, and densities ranging from those of gases to densities tens of times larger than those of a solid...
This volume began with an invitation from the publishers to edit a volume of EXS on Cancer.This invitation undoubtedly derived from my articles in Cellular and Molecular Life Sciences in 2002 and 2003 on the relationships between the morphology, aetiology and...
This book introduces major agent platforms, frameworks, systems, tools, and applications. Each system is described by their developers in sufficient detail so that the reader can get a good understanding of the architecture, functionality, and application areas of the...
During the first decades of the last century Italian mathematics was considered to be the third national school due to its importance and the high level of its numerous - searchers. The decision to organize the 1908 International Congress of Mathematicians in Rome...
Despite tremendous advances in the understanding of the sensory nervous system which have accompanied the recent explosive growth of the neurosciences, rema- ably few innovative medicines directed towards pain and inflammation are ava- able. Indeed, many patients are...
The most urgently needed vaccines are those against poverty-related diseases such as tuberculosis, malaria and HIV. However, there is a considerable gap between the development of a vaccine and the implementation as a useful measure for disease control. Major obstacles...
Sodium channels confer excitability on neurons in nociceptive pathways and exhibit neuronal tissue specific and injury regulated expression. This volume provides recent insights into the control of expression, functioning and membrane trafficking of nervous system...
Poisson manifolds play a fundamental role in Hamiltonian dynamics, where they serve as phase spaces. They also arise naturally in other mathematical problems, and form a bridge from the "commutative world" to the "noncommutative world". The aim of this book is twofold:...
Thisvolumecontainsaselectionofpapersinmodernoperatortheoryanditsapp- cations. Most of them are directly related to lectures presented at the Fourteenth International Workshop on Operator Theory and its Applications (IWOTA 2003) held at the University of Cagliari, Italy,...
Alcoholism is a pathological behavioural syndrome, characterised by comp- sive alcohol use, craving and relapses, even recurring after many years of abstinence. It is suggested that chronic alcohol abuse leads to persistent changes within several neurochemical pathways...
Recent research indicates that the immune system and inflammatory reactions are governed and regulated by powerful neuronal mediators derived from the central and peripheral nervous system. The NPY family of peptides is a diverse group of neuropeptides that acts via...
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