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Regularly reviewing the "state-of-the-art" developments in the antiviral drug research field, this latest volume spans the conceptual design and chemical synthesis of new antiviral compounds. It discusses their structure-activity relationship, mechanism and targets of...
The success of any drug discovery project relies upon the quality of the lead that initiates the lead optimization process. What defines a 'quality lead', where these 'quality leads' come from and how one discovers them has been the subject of intense debate within the...
The dictionary will contain terms covering the following fields and subfields: Vitamin Technology: Vitamin biochemistry / Physiology; Origin of vitamins: natural, synthetic; Fat-soluble vitamins; Water-soluble vitamins; Vitamins as antioxidants; Vitamin deficiencies /...
Lead Molecules from Natural Products: Discovery and New Trends provides the reader with a thorough overview of current discoveries and trends in Natural Products research. This book consists of 22 chapters from well known scientists all over the world, with topics...
The perceived lack of drug discovery productivity in recent times has led to much debate in the pharmaceutical/biotechnology industry as escalating R&D costs are not being matched by increased output. Few observers doubt that selecting the right targets, ie those which...
Synthesis of Essential Drugs describes methods of synthesis, activity and implementation of diversity of all drug types and classes. With over 2300 references, mainly patent, for the methods of synthesis for over 700 drugs, along with the most widespread synonyms for...
Volume 28 in the series of Side Effects of Drugs Annuals (http://www.elsevier.com/locate/series/seda) continues to serve its primary goal: to provide clinicians and medical investigators with a reliable and critical yearly survey of new data and trends in the area of...
The fourth volume of Advances in Antiviral Drug Design is keeping up with the recent progress made in the broad field of antiviral drug research and encompasses six specific directions that have opened new avenues for the treatment of HIV and other virus...
The Side Effects of Drugs Annual was first published in 1977. It has been published continuously since then, as a yearly update to the encyclopaedic volume Meyler's Side Effects of Drugs. Each new Annual provides clinicians and medical investigators with a reliable and...
This volume features accounts of the biological rationale, design and clinical potential of drug molecules; summaries of structure-activity relationships in topical areas of medicinal chemistry and extensive references to the biology, medicinal chemistry and clinical...
This volume covers contemporary advances in five important areas of pharmacology and medicinal chemistry including: a comprehensive account of inhibitors of the caspase family of proteolytic enzymes that represent a new class of anti-inflammatory and antiapoptotic...
The tradition of setting new trends in medicinal chemistry continued at the 13th Symposium where topics included chemical and biological diversity, new paradigms in drug action, and new insights in receptor mechanisms. Other topics of great interest discussed, and...
Progress in Medicinal Chemistry
Receptor Chemistry Towards the Third Millennium is the result of papers presented at the 12th Camerino-Noordwijkerhout Symposium, held in Camerino, Italy in September 1999. Although much is known about the way ligands interact with receptors, which have now been...
This volume reviews recent advances in five important areas of medicinal chemistry which will be of interest both to chemists and to scientists of other disciplines engaged in medicines research and development. Included are accounts of successful drug discovery...
Volume 3 of Advances in Antiviral Drug Design is keeping up with the recent progress made in the field of antiviral drug research and highlights five specific directions that have opened new avenues for the treatment of virus infections. First, the use of lamivudine...
Volume 4 of Advances in Medicinal Chemistry is comprised of six chapters on a wide range of topics in medicinal chemistry, including molecular modeling, structure-based drug design, organic synthesis, peptide conformational analysis, biological assessment,...
Eminent scientists at the cutting edge of pharmacology and medicinal chemistry research provide us with yet another excellent addition to this famous series. The focus on bacterial resistance mechanisms serves to highlight an important area of unmet medical need...
For twenty years this book, now in its 5th edition, has provided information on adverse drug interactions that is unrivalled in coverage and scholarship.Adverse drug reactions, many of them ascribable to interactions with other drugs or with chemical substances in food...
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