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In mathematics, it simply is not true that 'you can't prove a negative'. Many revolutionary impossibility theorems reveal profound properties of logic, computation, fairness and the universe, and form the mathematical background of new technologies and Nobel prizes. But...
Integer linear programming (ILP) is a versatile modeling and optimization technique that is increasingly used in non-traditional ways in biology, with the potential to transform biological computation. However, few biologists know about it. This how-to and why-do text...
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