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TGF-beta, originally identified as a transforming growth factor with similar properties, is now known to exist as a family of factors with similar properties. These factors promote cell proliferation in some tissue types or conditions and induce cell differentiation in...
Myopia, the most common disorder of the eye, affects 80% of the population of some countries. Although its basis remains uncertain, recent development of animal models have permitted tests of hypothesis as to myopia's origins. The symposium proceedings cover normal...
Modern technology has made possible epidemiological studies that relate aspects of neonatal health to disease in adult life. This symposium is the first to draw together information from this new research area. Explores links between early growth and the risk of high...
As part of a continuing effort to tackle issues of major social concern, this 280th conference of internationally recognized experts from the fields of molecular biology, medicine, philosophy, theology, and the law looks into the scientific, legal, ethical, social, and...
Certain organic compounds can become toxic to biological tissue when activated by light. Many medical applications of this effect have been studied over the past twenty years, and This symposium brings together chemists, biologists, and clinicians to discuss the basic...
Presented here are the most up-to-date research findings of leading international scientists in the field of aging. The collected data explores the biological, medical, and chemical implications and the latest thinking on the role of proto-oncogenes and their...
This work deals with basic plant physiology and cytology, and addresses the practical exploitation of plants, both as crops and as sources of useful compounds produced as secondary metabolites. Covers problems of commercial exploitation, socio-legal aspects of genetic...
An international group of researchers addresses basic mechanism involved in the metastatic spread of tumors and considers new methods of prevention and treatment. Compares behavior of normal and abnormal cells, with emphasis on cell surface mechanisms--especially...
Many common human diseases have a multifactorial origin: they are influenced by a person's genetic predisposition as well as by factors in the environment. This volume deals with the application of recombinant DNA techniques to the identification of diseases that have...
Comprises the proceedings of a symposium held at the Ciba Foundation, London, February 1988. Contains the latest research results on the inverse relationship between cell proliferation and differentiation and the nature of the genes involved. Included are the studies of...
Until recently a neglected disease syndrome, diarrhea is responsible for many millions of infant deaths in developing countries. The result of a 1987 symposium, this volume reflects advances in the aetiology of diarrhea while addressing such puzzling problems as the...
Regulation of intracellular pH is vital to all living cells. This symposium covers the control of pH in muscle and nerve cells and the different mechanisms of acid transport across epithelial and other cell membranes. Papers describe the development and application of...
Epithelial cells cover the outer and inner surfaces of the body, forming a selective polarized barrier between the intercellualar space and the 'external' world. Linking the cells of this continuous layer and contributing to epithelial organization and function are...
Dietary supplements can contain a wide variety of ingredients, either singly or in combination, including nutrients, botanicals and 'bioactive components' commonly found in foods. They are marketed and used by consumers for a range of reasons: to enhance "well-being",...
Much recent research in evolutionary developmental biology has focused on the origin of new body plans. However, most evolutionary change at the population and species level consists of tinkering: small-scale alterations in developmental pathways within a single body...
This book explores existing and potential strategies for using the genome sequences of human, mouse, other vertebrates and human pathogens to solve key problems in the treatment of immunological diseases and chronic infections. The assembled genome sequences now...
Heart failure is the main cause of death and disability in the industrialized world. There is a major need for novel therapeutics for prevention and reversal of cardiac pathology associated with heart failure and cardiac enlargement. Over recent years, dramatic progress...
Dengue virus is a member of the Flaviviridae family, which includes viruses associated with human diseases such as yellow fever, Japanese encephalitis and hepatitis C. Dengue fever is transmitted by mosquitoes, principally Aedes aegypti. There are four serotypes of...
This book features scientists from a broad spectrum of disciplines discussing recent data on aggression in laboratory animals with particular reference to possible implications for understanding human aggression. Chapters focus on the major current experimental issues...
This book features contributions from experts in cell biology, genetics, neurobiology, immunology and structural biology. The unifying element is that they all study processes of cell shape change and motility. Several key questions in this field of research are...
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