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Percutaneous left atrial appendage (LAA) closure is an emerging technology for thromboembolic prevention in patients with atrial fibrillation (AF). The first human implantation of an LAA device occurred in 2001, and since then four devices have received CE mark...
This book focuses on data describing the roles of free radicals and related reactive species, and antioxidants, in the causes and treatments of diseases, examining both clinical and pre-clinical trials, as well as basic research. The book is divided into sub-sections...
Cognitive Behavioral Therapy (CBT) has a growing evidence base that supports its efficacy in treating a wide range of psychiatric disorders and has been adapted for use with more complicated patient populations and for different stages of psychiatric illness. As the...
This book presents an up-to-date and comprehensive review of female contraception. It offers an extensive overview of contraception types, including oral, injectable, emergency, and various cervical barrier contraceptives, as well as behavioral and sterilization...
This book surveys the normal obstetrics encountered in primary care and serves as a practical guide to the evaluation and management of common prenatal, peripartum and postpartum complications. Thoroughly revised and updated, Obstetrics in Family Medicine, Second...
The second edition of this text presents an overview of the most recent developments in this area including clinical presentation, etiology, pathogenesis, and differential diagnosis.The rationale for various therapies, including transplantation, is discussed and tissue...
As the first primer on the effects of exercise on human hypertension, Effects of Exercise on Hypertension: From Cells to Physiological Systems provides the state-of-the-art effects of exercise on the many possible mechanisms underlying essential hypertension in humans....
PARP Inhibitors for Cancer Therapy provides a comprehensive overview of the role ofPARP in cancer therapy. The volume covers the history of the discovery ofPARP (poly ADP ribose polymerase) and its role in DNA repair. In addition, a description of discovery of thePARP...
This volume examines the current state of free radical biology as it impacts on hepatic disorders. It takes a thorough look at the relationship of oxidative stress in acute and chronic disease and takes into account factors like: redox biomarkers; antioxidant defense...
This book provides an overview of pulmonary hypertensive diseases, the current understanding of their pathobiology, and a contemporary approach to diagnosis and treatment. It discusses the definition and classification of these disorders and the epidemiology of...
This volume presents a comprehensive overview of the latest advances in basic and translational research in the field of reconstructive transplantation and its potential therapeutic implications. Dr. Thomas E. Starzl and Dr. Raimund Margreiter, both pioneers in the...
Dyslipidemias: Pathophysiology, Evaluation and Management provides a wealth of general and detailed guidelines for the clinical evaluation and management of lipid disorders in adults and children. Covering the full range of common through rare lipid disorders, this...
This comprehensive volume examines the current state of free radical biology and its impact on otology, laryngology, and head and neck function. The chapters collectively highlight the interrelationship of basic and translational studies in each area, define the...
This book illustrates the imperative for late-life depression prevention, introducing a broad range of approaches to prevention and provides detailed examples of clinical applications of late-life depression prevention – all with consideration of medical and scientific,...
This book discusses the relationship between cellular immunity and tryptophan metabolism, as well as its products, serotonin and melatonin, in the development of several diseases and reappraises the common signal transduction pathways of the neurodegenerative diseases,...
Transitional Urology is designed to fill a critical gap that exists in the published literature by comprehensively addressing the urological challenges facing adolescents and adults with complex congenital anomalies of the genitourinary system. It provides a valuable...
This book serves as a timely and comprehensive overview of the latest science for perfluoroalkyl and polyfluoroalkyl substances (PFASs), covering the development of methods for assessing PFASs in biological fluids and tissues as well as the current knowledge regarding...
Advances in the technology used in personalized medicine and increased applications for clinical use have created a need for this expansion and revision of Kewal K. Jain’s Textbook of Personalized Medicine. As the first definitive work on this topic, this book reviews...
This volume provides readers a comprehensive and state-of-the-art overview about the range of applications of targeted therapies for solid tumors. The sections of the book have been structured to review the oncogene addicted tumors, the pharmacology and clinical...
This volume discusses the many ways to prevent, identify and control hypertension in African Americans, a common and potent risk factor for virtually all forms of cardiovascular-renal diseases. Comprehensive chapters address modifiable risk factors, such as lifestyle...
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