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The origin of modern intensive care units (ICUs) has frequently been attributed to the widespread provision of mechanical ventilation within dedicated hospital areas during the 1952 Copenhagen polio epidemic. However, modern ICUs have developed to treat or monitor...
For over 50 years, coronary angiography has been the mainstay of diagnosing and quantifying the extent of coronary artery disease. However appreciation of the inherent limitations of conventional angiography has led to a plethora of new imaging modalities, each with...
Clinical research in critical care has exploded in the past several years and we now have a much better understanding of how to care for intensive care unit (ICU) patients in areas such as management of sepsis, fluid resuscitation, mechanical ventilation, antibiotic...
This atlas contains more than 700 illustrations that the authors have collected over the years as well as references and information pertaining to recently developed drug classes, including biologics. It is a useful bench reference for practicing pathologists and may...
Integrative Weight Management: A Guide for Clinicians intends to educate physicians and nutritionists about the wide ranges of approaches to weight control from non-traditional sources. The options for weight management in conventional practices are limited to a small...
The field of adipose tissue biology has been expanding at a very rapid pace in the last few years. Numerous advances have been made since publication of the first edition of this book, in terms of basic adipocyte biology, understanding of the determinants of obesity,...
Adult Stem Cells, second edition, takes a critical look at issues concerning the developmental or differentiation potential for a variety of tissue types and for specific adult stem cell types. Since the first edition appeared a decade ago, our understanding of adult...
This volume covers data describing the role of free radicals and antioxidants in respiratory disorders, including the data that deal with clinical and pre-clinical trials. Chapters describe the relationship of oxidative stress to a number of respiratory and pulmonary...
Starting with discussion of basic concepts and the molecular mechanisms of necrosis, this book looks first at several forms of necrotic cell death that have been identified, including necroptosis, autophagic cell death, and PARP-mediated cell death. As necrotic cell...
This second edition addresses the complex, multifaceted relationships between nutrition and oral health, explores proposed relationships between oral, systemic and nutritional well-being and provides insights into interprofessional, comprehensive care for...
Minimally Invasive Therapy for Urinary Incontinence and Pelvic Organ Prolapse provides a detailed insight into “when, why, what and how” of various minimally invasive surgical procedures for surgical management of SUI, OAB & POP. The volume provides detailed...
The metabolic and health effects of both nutritive and non-nutritive sweeteners are controversial, and subjects of intense scientific debate. These potential effects span not only important scientific questions, but are also of great interest to media, the public and...
Studies on Diabetes examines how increased oxidative and nitrosative stress – one of the leading causes of diabetes complications – pathologically affects multiple tissues in the body. The volume editors and chapter authors are leading investigators in the field of...
Nutrition in Kidney Disease, Second Edition addresses the relationships between nutrition and (1) normal kidney function and disease, (2) the progressiveness of chronic kidney disease (CKD) and strategies to prevent further compromise, and (3) the treatment and...
The Handbook of Environmental Engineering series is an incredible collection of methodologies that study the effects of pollution and waste in their three basic forms: gas, solid, and liquid. This exciting new addition to the series, Volume 15: Modern Water Resources...
There are many steps on the road from discovery of an anticancer drug to securing its final approval by the Food and Drug Administration. In this thoroughly updated and expanded second edition of the Handbook of Anticancer Pharmacokinetics and Pharmacodynamics, leading...
The chapters of Studies on Periodontal Disease comprise four parts. Part 1 provides basic sciences from the general to the particular.The findings of cell culture and animal models supply the mechanism between periodontal disease and oxidative stress. In part 2, human...
Diabetes mellitus has become epidemic on a global scale, and millions of new cases are diagnosed every year. The epidemic of diabetes mellitus is expected to result in one of the steepest rises in human morbidity and mortality ever observed outside of wartime. Insulin...
In this volume, the major metabolic alterations identified in cancer and tumor-associated cells are explored, including discussions of former and emerging approaches to drug development in targeting cancer cell metabolism. The metabolic network in cells promotes the...
Celiac Disease is an authoritative text intended to educate healthcare practitioners, gastroenterologists, physicians and nutritionists about the diverse manifestations, complications and management of gluten-sensitive enteropathy. The seventeen-chapter text provides...
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