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This volume starts with an elementary introduction covering stem cell methodologies used to produce specific types of neurons, possibilities for their therapeutic use, and warnings of technical problems. In addition the authors report successes in achieving the...
This book brings together leading investigators who represent various aspects of brain dynamics with the goal of presenting state-of-the-art current progress and address future developments. The individual chapters cover several fascinating facets of contemporary...
Recent years have seen spectacular advances in the field of circadian biology. These have attracted the interest of researchers in many fields, including endocrinology, neurosciences, cancer, and behavior. By integrating a circadian view within the fields of...
This book has brought together leading investigators who work in the new arena of brain connectomics.This includes ‘macro-connectome’ efforts to comprehensively chart long-distance pathways and functional networks; ‘micro-connectome’ efforts to identify every neuron,...
This volume provides the reader with a pathophysiological perspective on the role of CNS in puberty and adolescence, starting from genetic/molecular aspects, going through structural/imaging changes and leading to physical/behavioral characteristics. Therefore, renowned...
The authors address in particular the role of hormones and their links with other maternal environmental mediators in developmental programming.The crucial nature of the placenta as an interface and target between maternal and foetal environments is addressed. Emphasis...
Traditionally, neuroscience has considered the nervous system as an isolated entity and largely ignored influences of the social environments in which humans and many animal species live. However, there is mounting evidence that the social environment affects behavior...
The recent advances in Programming Somatic Cell (PSC) including induced Pluripotent Stem Cells (iPS) and Induced Neuronal phenotypes (iN), has changed our experimental landscape and opened new possibilities.The advances in PSC have provided an important tool for the...
The misfolding and aggregation of specific proteins is an early and obligatory event in many of the age-related neurodegenerative diseases of humans.The initial cause of this pathogenic cascade and the means whereby disease spreads through the nervous system, remain...
In theoretical terms, sex differences in brains and behaviors of laboratory animals offer the possibility of fascinating scientific studies on a range of molecular phenomena such as genomic imprinting, DNA methylation, chromatin protein modification, non-coding DNA,...
The health of the proteome depends upon protein quality control to regulate the proper synthesis, folding, translocation, and clearance of proteins.The cell is challenged constantly by environmental and physiological stress, aging, and the chronic expressions of disease...
Recent years have seen spectacular advances in the filed of epigenetics. These have attracted the interest of researchers in many fields and evidence connecting epigentic regulation to brain functions has been accumulationg. Neurons daily convert a variety of external...
Fifteen of the foremost scientists in this field presented testable theoretical models of consciousness and discussed how our understanding of the role that consciousness plays in our cognitive processes is being refined with some surprising results.
Homeostasis involves a delicate interplay between generative and degenerative processes to maintain a stable internal environment. In biological systems, equilibrium is established and controlled through a series of negative feedback mechanisms driven by a range of...
Dans le domaine de la pensée, le XXe siècle n'est pas né en 1900, mais en 1859. Une année bien remplie : Napoléon III s'active, Cavour aussi, qui va unifier l'Italie. Mais, plus important encore, Marx publie sa Contribution à la critique de l'économie politique et...
Koko le gorille, Alex le perroquet, Ake le dauphin, et bien d'autres, ont prouvé aux scientifiques passionnés leur intelligence logique, langagière, sociale et affective. Ils jonglent avec les chiffres et les mots, pleurent leurs morts, chérissent leur famille : on...
« Déconstruire l’idée que l’animal serait sans intelligence, sans conscience, sans langage, etc., n’est qu’une étape vers une entreprise plus essentielle : la reconnaissance de la richesse des mondes animaux, dans leur diversité, sans céder à la tentation de les...
Longtemps nous avons considéré les animaux comme ceux que la nature avait privés des qualités que nous, les humains, possédons : l’aptitude à raisonner, apprendre, communiquer, s’adapter, décoder, transmettre, enseigner, progresser… Les travaux scientifiques ont...
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